Abnormal social behaviors in mice lacking Fgf17
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چکیده
منابع مشابه
Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.
SHANK3 is a synaptic scaffolding protein enriched in the postsynaptic density (PSD) of excitatory synapses. Small microdeletions and point mutations in SHANK3 have been identified in a small subgroup of individuals with autism spectrum disorder (ASD) and intellectual disability. SHANK3 also plays a key role in the chromosome 22q13.3 microdeletion syndrome (Phelan-McDermid syndrome), which inclu...
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TFIID is a general transcription factor required for transcription of most protein-coding genes by RNA polymerase II. TAF7L is an X-linked germ cell-specific paralogue of TAF7, which is a generally expressed component of TFIID. Here, we report the generation of Taf7l mutant mice by homologous recombination in embryonic stem cells by using the Cre-loxP strategy. While spermatogenesis was complet...
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ژورنال
عنوان ژورنال: Genes, Brain and Behavior
سال: 2008
ISSN: 1601-1848,1601-183X
DOI: 10.1111/j.1601-183x.2007.00357.x